Three Fugitives

Three Fugitives is a 1989 crimecomedy film written and directed by Francis Veber, starring Nick Nolte and Martin Short, and featuring Sarah Rowland Doroff, James Earl Jones and Alan Ruck in supporting roles. It is a remake of Les Fugitifs, a 1986 French comedy starring Grard Depardieu and Pierre Richard also directed by Veber.

Detective Duggan Jones assumes they must be in it together and sets about tracking them down. Several chases, an accidental shooting, treatment from a crazy vet who thinks hes a dog and other capers follow, all the while Lucas trying to ditch his idiotic companion and prove his own innocence.Whilst avoiding the law, the two form an unlikely partnership to help cure the silent Meg and make good their escape. They rescue Meg from the care home shes in with Perry nearly ruining the whole affair with his clumsiness and flee for Canada, pretending to be a married couple with a son. ........

Source: Wikipedia